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Some metals contain tungsten carbide nanoparticles (WC-NPs), which can leach into waterways and soils via wastewater. In a 2018 study, Mikael T. Ekvall and colleagues found that WC-NPs can accumulate in the bodies of water lice (_Asellus aquaticus_). While bioaccumulation of manufactured nanoparticles may be inherently worrisome, it has been hypothesized that WC-NP bioaccumulation in invertebrates like _A. aquaticus_ could serve a valuable proxy role, obviating the need for manufacturers to conduct costly and intrusive sampling of vertebrate species—such as Perez's frogs (_Pelophylax perezi_), commonly used in regulatory compliance testing—for nanoparticle bioaccumulation, as environmental protection laws currently require.