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Northeastern Kansas's Jefferson County is among the most rural counties in the United States: the US Census Bureau classified it as 98.8% rural in 2010. Researchers studying populations of counties like Jefferson often struggle to recruit and retain participants. Melissa Valerio and colleagues tested whether a method called snowball sampling could improve recruitment and retention. Working in two rural counties, the researchers identified a small number of people who had the characteristics desired for a proposed study and asked them to recruit additional participants from their social networks. Valerio and colleagues found that participants recruited via snowball sampling showed a much higher retention rate than did people recruited by strangers, suggesting that