Source Texts
Text
Students in a biology class investigated why individual house mice (Mus musculus) can differ from one another in their circulating sodium level. The students compared wild-type mice and knockout mice, which are mice with specific genes deactivated, when mice of each type were placed in similar naturalistic environments and taken for periodic blood sampling. Finding that knockout mice with the gene Asb5 deactivated tended to have lower concentrations of sodium in their blood than did wild-type mice, the students concluded that differences in circulating sodium level among house mice in nature are solely attributable to variations in the level of expression of Asb5.