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Biologist Rosanna Alegado believes that we might learn how multicellular organisms developed from single-celled ones if we understand why the single-celled organism Salpingoeca rosetta, the oldest living relative of animals, sometimes forms colonies of cells. Alegado and colleagues reviewed data from many studies of how S. rosetta responds when exposed to another type of single-celled organism, bacteria, including Tristan Barbeyron's work with Zobellia galactonovorans bacteria and Yoshihide Matsuo's work with Zobellia uliginosa bacteria. Alegado and colleagues concluded that both Z. galactonovorans and Z. uliginosa might have played a role in the development of multicellular organisms.