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The synthesis of novel superheavy elements, such as nihonium (Nh), has led theorists to consider the feasibility of synthesizing all possible chemical compounds. In 2022, Guillermo Restrepo calculated the historical rates at which newly discovered compounds have entered the scientific literature, expanding the "chemical space." Using a conservative estimate of the number of viable compounds and assuming a doubling of the historical pace of discovery, Restrepo found that uraer these hypothetical conditions, all potential compounds could be synthesized and documented by 2050.