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In 2011 Brynn M. Devine and colleagues published a study concluding that ocean acidification has a strong effect on the behavior of Cheilodipterus quinquelineatus, a species of fish. However, Devine and colleagues' study relied on a mean sample size of only about 25 fish. In a 2022 review of various scientists' conclusions about the impacts of ocean acidification on fish behavior, Timothy D. Clark and colleagues caution that relying on such a relatively small sample size can increase the potential for biased analysis. Such analysis, in turn, can contribute to reports of exaggerated effects.